Background
People Living With HIV/AIDS are at a higher risk of developing TB due to their compromised immune system. Isoniazid (INH) preventive therapy is a recommended strategy for preventing tuberculosis (TB) among people living with HIV (PLHIV). However, active TB may still occur after INH completion.

Aim and objectives

This present study aimed to assess the prevalence of active Tuberculosis among adults with HIV that had completed Isoniazid prophylaxis at Mitooma Health Centre IV in 2022.

Methodology
A cross-sectional descriptive design study was carried out to assess the prevalence of active tuberculosis in HIV adults who completed Isoniazid prophylaxis at Mitooma Health Center IV at an HIV care clinic. Descriptive statistics were used to summarize the data, and correlation analysis was performed to identify the prevalence of active tuberculosis among adults with human immunodeficiency virus who completed Isoniazid prophylaxis at Mitooma Health Center IV and factors associated with active TB after INH completion.
Results
This study found a low prevalence of active TB (25%) among adults with HIV/AIDS before starting Isoniazid prophylaxis. Significant correlations were found between co-morbidities (hypertension, diabetes mellitus, and cryptococcal meningitis) and active TB after INH completion (r=0.557, p