The raft forming system is one of the most practical and favoured methods for generating a long-lasting and predictable medication delivery profile in the GI tract. To overcome the limits of existing oral drug delivery methods, a gastro retentive drug delivery system has been developed, which has the potential to revolutionise medication and provide a variety of therapeutic benefits. Many obstacles face the gastro-retentive drug delivery system, which can be overcome by a new approach called the raft forming system. This method is used to deliver antacids and medications for the treatment of gastrointestinal infections and diseases. The mechanism of this system entails the formation of a viscous cohesive gel in contact with stomach fluids, in which each particle of the liquid expands in contact with gastric fluids, forming a continuous layer known as ";;;;;;;;;RAFT.";;;;;;;;; Because of the low bulk density caused by the production of carbon dioxide, this raft floats in gastric juices.

This technique can release a pharmacological molecule continuously, resulting in usually constant plasma profiles. By localising the drug to the site of action, lowering the dose required, or delivering uniform drug administration, the goal of this system's design is to reduce dosing frequency or increase therapeutic effectiveness.