Chlorhexidine versus Povidone-Iodine for the prevention of Surgical Site Infections: A review.
Abdullah Mohammed A Alzahrani, Meshari Ibrahim A Alayshan, Abdullah Alturqi K Alanazi, Ali Nuwaysir S. Alruwaili, Mohammed Amid S Alkhaldi, Amer Abdulaziz H Alharbi, Fahad Hammad F Alrayes, Saleh Abdullah S Almoallem, Mohammed Hamoud E Alkhaldi, Fahad Ghuwayli M Aljabri, Ahmad Saleh A Alrwaili, Alhanouf Abdullah Alatawi, Nawal Ali S Alharthi, Reuof Salem A Alamri, Renad Mohammed H Alanazi, Ibrahim Mahmoud H Ajwah
Abstract
Background
Surgical Site Infections (SSIs) are the third most frequently reported health care-associated infection and it remain a major clinical problem despite improvements in prevention, as they are associated with significant mortality and morbidity. Prevention strategies for SSIs are based on reducing the risk of infection by bacteria, So many antiseptic agents are used, the most common one are Chlorhexidine and Povidone-Iodine.
Aims
To discuss the findings of RCTs that compare Chlorhexidine versus Povidone-Iodine in the prevention of Surgical Site Infections (SSIs).
Methods
This systematic review was carried out, including PubMed, Google Scholar, and EBSCO that examining randomized trials of Chlorhexidine and Povidone-Iodine to summarize the major RCT that compare Chlorhexidine versus Povidone-Iodine in the prevention of Surgical Site Infections (SSIs).
Results
The review included six randomized studies that compare between Chlorhexidine and Povidone-Iodine for the prevention of SSIs. The findings showed that many studies prefer using Chlorhexidine over Povidine-Iodine to reduce SSIs, few studies prefer using PVI as antiseptic and other studies reported that there is no significant difference between both.
Conclusion
Majority of results prefer using Chlorhexidine than Povidone-Iodine as antiseptics but there were few findings prefer PVI and other studies reported that there was no significant difference between using them as antiseptics.
Full Text:
Surgical Site Infections (SSIs) are the third most frequently reported health care-associated infection and it remain a major clinical problem despite improvements in prevention, as they are associated with significant mortality and morbidity. Prevention strategies for SSIs are based on reducing the risk of infection by bacteria, So many antiseptic agents are used, the most common one are Chlorhexidine and Povidone-Iodine.
Aims
To discuss the findings of RCTs that compare Chlorhexidine versus Povidone-Iodine in the prevention of Surgical Site Infections (SSIs).
Methods
This systematic review was carried out, including PubMed, Google Scholar, and EBSCO that examining randomized trials of Chlorhexidine and Povidone-Iodine to summarize the major RCT that compare Chlorhexidine versus Povidone-Iodine in the prevention of Surgical Site Infections (SSIs).
Results
The review included six randomized studies that compare between Chlorhexidine and Povidone-Iodine for the prevention of SSIs. The findings showed that many studies prefer using Chlorhexidine over Povidine-Iodine to reduce SSIs, few studies prefer using PVI as antiseptic and other studies reported that there is no significant difference between both.
Conclusion
Majority of results prefer using Chlorhexidine than Povidone-Iodine as antiseptics but there were few findings prefer PVI and other studies reported that there was no significant difference between using them as antiseptics.
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