The role of Candida species in peri-implant diseases

Igor Smojver, Marko Vuletić, Mato Sušić, Luka Marković, Ivica Pelivan, Dragana Gabrić

Abstract

Background
Peri-implantitis is a chronic, marginal and progressive infection of soft and hard tissue that surrounds dental implants, which results in the loss of the supporting bone, caused by similar microbes as adult periodontitis. Staphylococcus aureus and Candida albicans are microorganisms that are not primarily associated with periodontitis, but certain studies identified them in peri-implant pockets.

Aims
The current review aimed to assess the role of Candida species in peri-implant diseases.

Methods
This review has been carried out in accordance with the question: ";;;What is the role of Candida albicans in peri-implant diseases?";;;. To answer this, a bibliographic search was carried out using PubMed, Scopus and Medline and it was limited to works published during 2009-2019.

Results
Candida albicans appears to play an important role in the formation and stabilization of biofilm on the titanium surfaces and in the implant itself, which subsequently allows the growth of periodontal pathogenic bacteria involved in the development of inflammatory response resulting in the loss of bone supporting the dental implant.

Conclusion
Further research is needed to shed more light on the pathophysiology of peri-implant inflammation and to find more effective ways to treat it.
Full Text: PDF