Epidemiology of frequent admitters of cardiovascular diseases in urbanizing Pune population
Syed Abrar Ahmad, Chandrakant Chavan, Rajesh Badani, Arundhati Diwan, Muthu Periasamy, Varsha Wankhade
Abstract
Background
Ischemic heart disease is known to be prevalent in Indian population
Aims
To study the prevalence of CVDs in Pune population and to elucidate comorbidities and the risk factors associated with frequently admitted CVD patients.
Methods
A descriptive cross-sectional study was carried out for a period of five years (2011–2015) in Pune India. Data was retrieved from Life Line software at Bharti Hospital. ICD-10 was followed throughout the study. Comorbidities and risk factors were estimated in frequent CVD admitters. For estimation of oxidative stress, antioxidant marker enzymes were estimated from plasma samples of CVD patients. Chi-square test was employed for the study of association in proportions. Kruskal-Wallis test was performed to test significance of difference.
Results
Among 939 cardiac patients, MI represented as the most common CVD especially in men (38.79 per cent). Higher level of Lipid peroxidation was reported in MI (14.43±1.82) than IHD (13.06±2.23), HCM (7±1.47) and control (2.44±0.74) (p < 0.001). MI patients show higher comorbidities and increased risk of developing complications. Glutathione reductase (U/mg) was decreased in MI (1.76±0.2) and HCM (1.8±0.3) patients than IHD (2.14±0.4) and Control samples (2.17±0.3) (p < 0.05).
Conclusion
MI is more often observed in frequent admitters of CVDs. IHD patients show higher comorbidities than other CVDs in this population. Oxidative stress was found to be more in MI than other cardiac disorders.
Full Text:
Ischemic heart disease is known to be prevalent in Indian population
Aims
To study the prevalence of CVDs in Pune population and to elucidate comorbidities and the risk factors associated with frequently admitted CVD patients.
Methods
A descriptive cross-sectional study was carried out for a period of five years (2011–2015) in Pune India. Data was retrieved from Life Line software at Bharti Hospital. ICD-10 was followed throughout the study. Comorbidities and risk factors were estimated in frequent CVD admitters. For estimation of oxidative stress, antioxidant marker enzymes were estimated from plasma samples of CVD patients. Chi-square test was employed for the study of association in proportions. Kruskal-Wallis test was performed to test significance of difference.
Results
Among 939 cardiac patients, MI represented as the most common CVD especially in men (38.79 per cent). Higher level of Lipid peroxidation was reported in MI (14.43±1.82) than IHD (13.06±2.23), HCM (7±1.47) and control (2.44±0.74) (p < 0.001). MI patients show higher comorbidities and increased risk of developing complications. Glutathione reductase (U/mg) was decreased in MI (1.76±0.2) and HCM (1.8±0.3) patients than IHD (2.14±0.4) and Control samples (2.17±0.3) (p < 0.05).
Conclusion
MI is more often observed in frequent admitters of CVDs. IHD patients show higher comorbidities than other CVDs in this population. Oxidative stress was found to be more in MI than other cardiac disorders.
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