Autoimmune Haemolytic Anemia is rarely associated with Ulcerative Colitis, and counts for just 0.2-0.7% of adult patient. It is a complication that is present by having a positive coombs test which account for only 1.82% in a patient with ulcerative colitis without any haemolytic evidence.

Hence there is only one case report has published the effective response to infliximab by both rare combined conditions.

Here we report the second case of sever ulcerative colitis associated with coombs positive autoimmune Haemolytic Anaemia (AIHA) response to infliximab.