Intra-luminal intestinal metastasis from malignant pleural mesothelioma

Raffaele Longo, Bruno Ribeiro Baptista, Marco Campitiello, Francesca Plastino, Nada Eid, Marie Caroline d’Huart, Laurence Klein, Eric Kull, Laurent Hennequin, Philippe Quétin


Malignant pleural mesothelioma (MPM) is a locally invasive tumour that rarely metastasises. Gastro-intestinal (GI) metastases from MPM are extremely uncommon. We present a case of a 73-year-old patient hospitalized for abdominal pain. Since a faecal occult blood test was positive, he underwent a colonoscopy identifying an intestinal adenocarcinoma. CT-scan showed a clinically asymptomatic right pleural tumour lesion histologically consistent with a MPM. A revision of the intestinal histology confirmed a metastasis from the MPM. The diagnosis of GI-MPM metastasis is challenging as it can be clinically and radiologically misdiagnosed. It should be considered in any patient with MPM history.
Full Text: PDF