Angle closure glaucoma secondary to psychotropic medications
John Ross Rocke, Roderick Francis Justin O'Day, Trent Courteney Roydhouse
Abstract
Background
Psychotropic medications are commonly associated anticholinergic side-effects. In susceptible patients, this can result in angle closure induced permanent loss of vision
Aims
To review the mechanism of angle closure and which psychotropics are most likely to precipitate this complication.
Methods
Literature review surrounding the mechanism of angle closure and pharmacology of various psychotropics
Results
Mydriasis, forward-displacement of the lens-iris diaphragm and ciliary body swelling are the mechanisms by which angle closure occurs. Anticholinergic side effects of psychotropic medications are most implicated in causing this.
Conclusion
Screening patients for risk factors of angle closure and either having them formally assessed or choosing psychotropics with minimal anticholinergic effects may avoid inducing angle closure.
Full Text:
Psychotropic medications are commonly associated anticholinergic side-effects. In susceptible patients, this can result in angle closure induced permanent loss of vision
Aims
To review the mechanism of angle closure and which psychotropics are most likely to precipitate this complication.
Methods
Literature review surrounding the mechanism of angle closure and pharmacology of various psychotropics
Results
Mydriasis, forward-displacement of the lens-iris diaphragm and ciliary body swelling are the mechanisms by which angle closure occurs. Anticholinergic side effects of psychotropic medications are most implicated in causing this.
Conclusion
Screening patients for risk factors of angle closure and either having them formally assessed or choosing psychotropics with minimal anticholinergic effects may avoid inducing angle closure.
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