Ultrasound-guided percutaneous treatment of liver hydatid cysts using 3% hydrogen peroxide as a scolicidal agent
Tawfik JM Al-marzooq, Qays A. Hassan, Mumtaz KH Alnaser
Abstract
Background
Hydatid disease of the liver is endemic in cattle areas of the world. A variety of treatment options is available. The common treatment options are medical therapy, surgery and puncture-aspiration-injection-reaspiration (PAIR) therapy.
Aims
To evaluate the clinical outcomes and effectiveness of PAIR therapy in the treatment of liver hydatid disease using 3 per cent hydrogen peroxide (HP) as a scolicidal agent.
Methods
Between October 2012 and October 2015, seventy hydatid cysts in 52 patients were treated by PAIR procedure using three per cent HP as a scolicidal agent. Pre-procedural clinical, radiological and laboratory characteristics and post-procedural morbidity, mortality and length of hospital stay were recorded.
Results
We performed PAIR of 70 hydatid cysts in 52 patients with a success rate of 95 per cent without any mortality. The mean length of hospital stay was three days (ranges 1–8). In our series, minor complications occurred in six patients and major complications in five patients. The follow-up period ranged from 12–18 months, with a mean of 15.3 months. Three patients developed recurrence.
Conclusion
PAIR therapy is a minimally invasive procedure for Gharbi type I-III hepatic hydatid cysts. It is a relatively safe procedure with a significant reduction in the duration of hospital stay. We believed that HP by itself plays a role in influencing the results and the outcomes of PAIR.
Full Text:
Hydatid disease of the liver is endemic in cattle areas of the world. A variety of treatment options is available. The common treatment options are medical therapy, surgery and puncture-aspiration-injection-reaspiration (PAIR) therapy.
Aims
To evaluate the clinical outcomes and effectiveness of PAIR therapy in the treatment of liver hydatid disease using 3 per cent hydrogen peroxide (HP) as a scolicidal agent.
Methods
Between October 2012 and October 2015, seventy hydatid cysts in 52 patients were treated by PAIR procedure using three per cent HP as a scolicidal agent. Pre-procedural clinical, radiological and laboratory characteristics and post-procedural morbidity, mortality and length of hospital stay were recorded.
Results
We performed PAIR of 70 hydatid cysts in 52 patients with a success rate of 95 per cent without any mortality. The mean length of hospital stay was three days (ranges 1–8). In our series, minor complications occurred in six patients and major complications in five patients. The follow-up period ranged from 12–18 months, with a mean of 15.3 months. Three patients developed recurrence.
Conclusion
PAIR therapy is a minimally invasive procedure for Gharbi type I-III hepatic hydatid cysts. It is a relatively safe procedure with a significant reduction in the duration of hospital stay. We believed that HP by itself plays a role in influencing the results and the outcomes of PAIR.
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