Multi-drug resistant Acinetobacter species from various clinical samples in a tertiary care hospital from South India
Vijayan Sivaranjani, Sivaraman Umadevi, Sreenivasan Srirangaraj, Arunava Kali, Kunigal S Seetha
Abstract
Background
Acinetobacter species are gram-negative coccobacilli belonging to the group of Non-Fermenting Gram-Negative Bacilli, which are ubiquitous in nature. They cause outbreaks in intensive care units and healthcare settings, and are becoming increasingly drug resistant.
Aims
To determine the prevalence of multi-drug resistant Acinetobacter species from various clinical samples.
Method
Clinical samples were processed as per standard microbiological techniques. Antibiotic susceptibility testing was carried out on all the Acinetobacter isolates by Kirby-Bauer disc diffusion method as per CLSI guidelines.
Results
A total of 122 Acinetobacter spp. were isolated. 110 (90.16 per cent) were from in-patients, and 12 (9.83 per cent) were from out-patients. Out of 122 isolates, 44 (36.06 per cent) were from ICU. The majority of the isolates, 47 (38.52 per cent), were from pus samples followed by 25 (20.49 per cent) from endotracheal tube aspirate. Out of 122 isolates, 87 (71.31 per cent) were multi-drug resistant of which 15 (12.29 per cent) were resistant to all drugs tested.
Conclusion
Acinetobacter infections associated with multi-drug resistant and pan-resistant strains have emerged as important nosocomial pathogens in our setting.
Full Text:
Acinetobacter species are gram-negative coccobacilli belonging to the group of Non-Fermenting Gram-Negative Bacilli, which are ubiquitous in nature. They cause outbreaks in intensive care units and healthcare settings, and are becoming increasingly drug resistant.
Aims
To determine the prevalence of multi-drug resistant Acinetobacter species from various clinical samples.
Method
Clinical samples were processed as per standard microbiological techniques. Antibiotic susceptibility testing was carried out on all the Acinetobacter isolates by Kirby-Bauer disc diffusion method as per CLSI guidelines.
Results
A total of 122 Acinetobacter spp. were isolated. 110 (90.16 per cent) were from in-patients, and 12 (9.83 per cent) were from out-patients. Out of 122 isolates, 44 (36.06 per cent) were from ICU. The majority of the isolates, 47 (38.52 per cent), were from pus samples followed by 25 (20.49 per cent) from endotracheal tube aspirate. Out of 122 isolates, 87 (71.31 per cent) were multi-drug resistant of which 15 (12.29 per cent) were resistant to all drugs tested.
Conclusion
Acinetobacter infections associated with multi-drug resistant and pan-resistant strains have emerged as important nosocomial pathogens in our setting.
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