Anxiety and depression are more common among diabetic patients than general population and can impact on treatment. The aim of this study is to screen a random selection of diabetic patients attending the diabetes clinic of Shahid Mohammadi hospital, Iran for anxiety and depression. 100 patients were surveyed using a valid and reliable measure for anxiety and depression. Data analyzed using SPSS 13 software. Prevalence of depression and anxiety was 50 and 67 percent respectively. Both depression and anxiety was more common among female patients, those with type 2 diabetes and those had at least one complication of diabetes. We report a very high prevalence of anxiety and depression in these patients. Routine assessment and treatment for anxiety and depression is indicated. Further research on the reason for the high incidence of depression in this patient group is warranted.