Table of contents (Vol 9, No 6)
EDITORIAL

Defragmenting health care for patients with chronic obstructive pulmonary disease
 

This editorial highlights the importance of defragmenting health care through an integrated approach and sharing of clinical information.

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By Claudia C Dobler

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RESEARCH

Clinical profile of high-risk febrile neutropenia in a tertiary care hospital
 

Febrile neutropenia is the most important factor for predisposition of infection in patients with malignancies irrespective of it being haematological or solid tumours. This study explains that, causative pathogen is constantly changing and hence identification and empirical treatment of the same can increase the rate of survival.

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By Mohan V Bhojaraja, Joseph Thomas, Mukhyaprana Prabhu M, Sushma T Kanakalakshmi

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Immunosuppressive drug assaying: A challenge for renal transplantation
 

In Australia, renal transplant patients of the Northern Territory (NT), suffer poor transplant outcomes including graft rejection, infection and increased mortality, therefore requiring stringent immunosuppressive drug assay monitoring.

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By Francesca Gagliardo, Kerry Dole, Sandawana William Majoni

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Do interpersonal problems catalyse experimentation of substance use among adolescents?
 

Adolescence is defined as a transitional phase from childhood to adulthood.  Prevalence and sociocultural determinants for substance experimentation and use among adolescents is being reported in this study.

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By Kallol Roy, Asha Kamath, Asha Hegde

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Characterization and lytic activity of methicillin-resistant Staphylococcus aureus(MRSA)
 

Methicillin-resistant Staphylococcus aureus (MRSA) is a well-known pathogen that causes serious diseases in humans. In this study, two phages were isolated and characterized from a NICU bathroom sink, from the Siphoviridae family, which specifically targets methicillin-resistant Staphylococcus aureus (MRSA).

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By Golnar Rahimzadeh, Mohammad Sadegh Rezai, Pooria Gill

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A single qualitative study can show same findings as years of quantitative research: Obstructive Sleep Apnea as an example
 

This study illustrates that many years of quantitative research led to our present knowledge of the symptoms and associated features (S&AF) of the obstructive sleep apnoea (OSA) syndrome.

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By Howard Tandeter, Yael Hershkovitz, Lea Kacen Kacen

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BRIEF REPORT

Acute myeloid leukaemia presenting as bilateral proptosis in a young child
 

This report illustrates a paediatric case presenting with bilateral proptosis, by using a peripheral blood smear (PBS) examination.

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By Charudutt Kalamkar, Dinesh Raj, Nishant Radke, Amrita Mukherjee

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CASE STUDY

A novel variant of the AGPAT2 mutation in generalized congenital lipodystrophy
 

Congenital generalised lipodystrophy (CGL) is a rare autosomal recessive lipodystrophy. Genetic analysis using Next Generation Sequencing (NGS) may help in identifying the mutated genes in patients presenting with characteristic clinical phenotype of inherited lipodystrophies.

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By Sahana Shetty, Aaron Chapla, Nitin Kapoor, Nihal Thomas, Thomas Vizhalil Paul

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Half and half nail or Lindsay’s nail
 

This case study highlights that, half and half nail serves as an important clue in making the diagnosis of chronic kidney disease. Also, whenever the previous creatinine reports are unavailable one can rely on this clinical sign in diagnosing end stage renal diseas.

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By Sharath Madhyastha, Vinaya Gopalaswamy, Raviraj Acharya, Ragini Bekur

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LETTER TO THE EDITOR

Letter
 

Pretibial pitting oedema associated with hyperthyroidism

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By Hideaki Yamabe, Fumiko Kudo, Ikuyo Narita, Michiko Shimada

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