A case control study of risk factors of coronary heart disease among patients admitted at tertiary hospital in western India

Malay B Shah, Vihang S Mazumdar, Sangeeta V Patel, Rajendra K Baxi, Kalpita K Shringarpure

Abstract

Background
Coronary heart disease (CHD) is a major cause of death in the world. In this study, various risk factors of CHD were explored.

Aims
To find out association of CHD with its risk factors in Western India.

Methods
A 100 cases of first episode of Acute Coronary Syndrome (ACS) patients and 200 age and sex matched controls from medical wards of a government run tertiary care hospital were interviewed through modified WHO STEPS questionnaire along with physical examination and anthropometric measurements. Data was cleaned and analysed through SPSS.

Results
On bivariate analysis current smoking status [OR=2.906 (1.69–4.98)], BMI [OR=2.6492 (1.49–4.72)], waist circumference [OR=1.7051 (1.01–2.88)] and positive family history [OR=2.0457 (1.07–3.91)] were found to be significantly associated with ACS cases. On multivariate analysis, BMI [OR=2.612 (1.376–4.959)] and current smoking status [OR=3.005 (1.791–5.042)] were found to be significantly associated with ACS cases.

Conclusion
Out of conventional risk factors, BMI and current smoking status were the only risk factors which had positive association with CHD in this study.
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